Posts filed under ‘Transformative/Innovative/High Risk, High Reward Research’

Make high-impact research a priority, White House says

On July 21, the White House directed science agencies to focus research investments on areas of major societal need. In a memo from its Office of Management and Budget, the White House laid out a plan that aims to maximize the return on federal investments in science for the 2012 federal budget.

Continue Reading July 28, 2010 at 6:13 pm Leave a comment

NSF criticized at U.S. Senate hearing about innovation

Should National Science Foundation grants be tied to how well universities work with industry? During a June 22nd U.S. Senate subcommittee hearing on innovation, Robert Atkinson, president of the Information Technology and Innovation Foundation, criticized the NSF’s approach to funding research.

Continue Reading June 24, 2010 at 11:59 am Leave a comment

What makes DARPA so special?

On Jan. 7 at a meeting of the President’s Council of Advisors on Science and Technology, officials from the Defense Advanced Research Project Agency, known as DARPA, presented what they believed were the characteristics of this defense-oriented research agency that have allowed it to innovate and succeed over it’s decades-long history. Skeptical, PCAST members questioned DARPA officials about the true source of DARPA’s perceived success.

Continue Reading January 22, 2010 at 8:30 pm Leave a comment

Hearing on innovation offers divergent perspectives

On Oct. 8, in testimony before the House Committee on Science and Technology’s Research and Science Education Subcommittee, prominent witnesses from the scientific community expressed differing views about how the federal government can foster scientific innovation. While witnesses and subcommittee members agreed that supporting “high-risk, high-reward” research was important, there was little consensus about the best mechanisms to encourage groundbreaking science.

Continue Reading October 26, 2009 at 2:50 pm 1 comment


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  • Rutgers team discovers novel approach to stimulate immune cells
    Research builds towards potential treatment for immune diseases and cancer May 14 2012 — Researchers at Rutgers University have uncovered a new way to stimulate activity of immune cell opiate receptors leading to efficient tumor cell clearance. ARTICLE CAPSULE Opiate Antagonist Prevents µ- and δ-Opiate Receptor Dimerization to Facilitate Ability of Agonist t […]
  • JBC Podcast: single-stranded DNA scanning enzymes
    A discussion with Myron Goodman and David Rueda May 4 2012 — In this podcast we hear an interview with Myron Goodman from the University of Southern California and David Rueda from Wayne State University who talk about the collaboration which led to their JBC Paper of the Week Singled-stranded DNA Scanning and Deamination by APOBEC3G at Single Molecular Reso […]
  • Researchers gain better understanding of mechanism behind tau spreading in the brain
    And the progression of Alzheimer's disease May 2 2012 — Researchers at Mount Sinai School of Medicine have gained insight into the mechanism by which a pathological brain protein called tau contributes to the progression of Alzheimer's disease (AD) and other neurodegenerative disorders This finding published in the most recent issue of The Journal […]
  • Online Now: May 2012 issue of ASBMB Today
    May 2 2012 – In this month's issue of ASBMB Today science writer Raj Mukhopadhyay profiles scientist-turned-artist Robert Schimke who once served as president of ASBMB and as an editorial board member for the Journal of Biological Chemistry Know a student who is graduating? ASBMB Today contributor Connor Bamford lists his top-10 picks for graduation gif […]
  • TssM is an energizer of a bacterial type VI secretion system
    Important for organism’s its ability to transfer DNA into plants May 1 2012 — Erh-Min Lai’s laboratory at Taiwan’s Institute of Plant and Microbial Biology has reported the energetic role of TssM in the type VI secretion system (T6SS) of Agrobacterium tumefaciens a plant pathogen and important organism for biotechnology because of its ability to transfer DNA […]

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